Dooley, Colette: search on Z-Library

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1

Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery

Houghten, Richard A., Pinilla, Clemencia, Blondelle, Sylvie E., Appel, Jon R., Dooley, Colette T., Cuervo, Julio H.

Journal:

Year:

1991

File:

PDF, 449 KB

1991

2

Peptide, peptidomimetic, and organic synthetic combinatorial libraries

Jutia Eichler, Jon R. Appel, Sylvie E. Blondelle, Colette T. Dooley, Barbara Döurner, John M. Ostresh, Enrique Péarez-Payá, Clemencia Pinilla, Richard A. Houghten

Journal:

Medicinal Research Reviews

Year:

1995

Language:

english

File:

PDF, 1.01 MB

english, 1995

3

Use and Implications of the Harmonic Mean Model on Mixtures for Basic Research and Drug Discovery

Santos, Radleigh G., Giulianotti, Marc A., Dooley, Colette T., Pinilla, Clemencia, Appel, Jon R., Houghten, Richard A.

Journal:

ACS Combinatorial Science

Year:

2011

Language:

english

File:

PDF, 2.14 MB

english, 2011

4

Versatility of positional scanning synthetic combinatorial libraries for the identification of individual compounds

Clemencia Pinilla, Jon R. Appel, Sylvie E. Blondelle, Colette T. Dooley, Jutta Eichler, John M. Ostresh, Richard A. Houghten

Journal:

Drug Development Research

Year:

1994

Language:

english

File:

PDF, 1.25 MB

english, 1994

5

A Novel Method for the Determination of Isokinetic Ratios and Its Application in the Synthesis of Two New Positional Scanning Libraries

Giulianotti, Marc A., Debevec, Ginamarie, Santos, Radleigh G., Maida, Laura E., Chen, Wenteng, Ou, Lili, Yu, Yongping, Dooley, Colette T., Houghten, Richard A.

Journal:

ACS Combinatorial Science

Year:

2012

Language:

english

File:

PDF, 3.38 MB

english, 2012

6

Orphanin FQ/Nociceptin receptor binding studies

Colette T. Dooley, Richard A. Houghten

Journal:

Year:

2000

Language:

english

File:

PDF, 194 KB

english, 2000

7

The use of positional scanning synthetic peptide combinatorial libraries for the rapid determination of opioid receptor ligands

Colette T. Dooley, Richard A. Houghten

Journal:

Year:

1993

Language:

english

File:

PDF, 531 KB

english, 1993

8

Synthesis and analgesic activity of alkylated, reduced and constrained oligoheterocyclic peptidomimetic analogs of Leu-enkephalin

Hammami, Saoussen, Mighri, Zine, Dooley, Colette T., Nefzi, Adel

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 560 KB

english, 2014

9

Bridging immunogenetics and immunoproteomics: Model positional scanning library analysis for Major Histocompatibility Complex class II DQ in Tursiops truncatus

Dooley, Colette T., Ferrer, Tatiana, Pagán, Heidi, O’Corry-Crowe, Gregory M., Colombo, Gualtiero I.

Journal:

Year:

2018

Language:

english

File:

PDF, 9.64 MB

english, 2018

10

In vitro and direct in vivo testing of mixture-based combinatorial libraries for the identification of highly active and specific opiate ligands

Richard A. Houghten, Colette T. Dooley, Jon R. Appel

Journal:

The AAPS Journal

Year:

2006

Language:

english

File:

PDF, 244 KB

english, 2006

11

The pharmacological properties of a novel MCH1 receptor antagonist isolated from combinatorial libraries

Hiroshi Nagasaki, Shinjae Chung, Colette T. Dooley, Zhiwei Wang, Chunying Li, Yumiko Saito, Stewart D. Clark, Richard A. Houghten, Olivier Civelli

Journal:

European Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 821 KB

english, 2009

12

Antinociceptive Activity of Thiazole-containing Cyclized DAMGO and Leu-(Met) Enkephalin Analogs

Harris, Hannah, Davis, Jennifer, Eans, Shainnel, Ganno, Michelle L., Dooley, Colette, McLaughlin, Jay P., Nefzi, Adel

Journal:

Organic & Biomolecular Chemistry

Year:

2019

Language:

english

File:

PDF, 1.08 MB

english, 2019

13

Ligand/kappa-opioid receptor interactions: Insights from the X-ray crystal structure

Martinez-Mayorga, Karina, Byler, Kendall G., Yongye, Austin B., Giulianotti, Marc A., Dooley, Colette T., Houghten, Richard A.

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.10 MB

english, 2013

14

Imaging Dynamic Redox Changes in Mammalian Cells with Green Fluorescent Protein Indicators

Dooley, Colette T., Dore, Timothy M., Hanson, George T., Jackson, W. Coyt, Remington, S. James, Tsien, Roger Y.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 1.10 MB

english, 2004

15

The use of synthetic peptide combinatorial libraries for the determination of peptide ligands in radio-receptor assays: Opioid peptides

Richard A. Houghten, Colette T. Dooley

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 488 KB

english, 1993

16

Combinatorial chemistry: From peptides and peptidomimetics to small organic and heterocyclic compounds

Adel Nefzi, Colette Dooley, John M. Ostresh, Richard A. Houghten

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 313 KB

english, 1998

17

Strategies for the Use of Mixture-Based Synthetic Combinatorial Libraries: Scaffold Ranking, Direct Testing In Vivo, and Enhanced Deconvolution by Computational Methods

Houghten, Richard A., Pinilla, Clemencia, Giulianotti, Marc A., Appel, Jon R., Dooley, Colette T., Nefzi, Adel, Ostresh, John M., Yu, Yongping, Maggiora, Gerald M., Medina-Franco, Jose L., Brunner, Da

Journal:

Journal of Combinatorial Chemistry

Year:

2008

Language:

english

File:

PDF, 1.83 MB

english, 2008

18

Mixture-Based Synthetic Combinatorial Libraries

Houghten, Richard A., Pinilla, Clemencia, Appel, Jon R., Blondelle, Sylvie E., Dooley, Colette T., Eichler, Jutta, Nefzi, Adel, Ostresh, John M.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 3.69 MB

english, 1999

19

Potent μ-Opioid Receptor Agonists from Cyclic Peptides Tyr- c [ d -Lys-Xxx-Tyr-Gly]: Synthesis, Biological, and Structural Evaluation

Li, Yangmei, Cazares, Margret, Wu, Jinhua, Houghten, Richard A., Toll, Laurence, Dooley, Colette

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 895 KB

english, 2016

20

Identification, structure–activity relationships and molecular modeling of potent triamine and piperazine opioid ligands

Austin B. Yongye, Jon R. Appel, Marc A. Giulianotti, Colette T. Dooley, Jose L. Medina-Franco, Adel Nefzi, Richard A. Houghten, Karina Martínez-Mayorga

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 1.40 MB

english, 2009

21

ChemInform Abstract: Mixture-Based Synthetic Combinatorial Libraries

Richard A. Houghten, Clemencia Pinilla, Jon R. Appel, Sylvie E. Blondelle, Colette T. Dooley, Jutta Eichler, Adel Nefzi, John M. Ostresh

Journal:

Year:

1999

File:

PDF, 24 KB

1999

22

Conformation-opioid activity relationships of bicyclic guanidines from 3D similarity analysis

Karina Martínez-Mayorga, Jose L. Medina-Franco, Marc A. Giulianotti, Clemencia Pinilla, Colette T. Dooley, Jon R. Appel, Richard A. Houghten

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 423 KB

english, 2008

23

Identification of potent and highly selective chiral tri-amine and tetra-amine μ opioid receptors ligands: An example of lead optimization using mixture-based libraries

Adel Nefzi, John M. Ostresh, Jon R. Appel, Jean Bidlack, Colette T. Dooley, Richard A. Houghten

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 183 KB

english, 2006

24

Libraries from libraries: Generation and comparison of screening profiles

Richard A. Houghten, Sylvie E. Blondelle, Colette T. Dooley, Barbara Dörner, Jutta Eichler, John M. Ostresh

Journal:

Molecular Diversity

Year:

1996

Language:

english

File:

PDF, 344 KB

english, 1996

25

Parallel synthesis of bis-oxazole peptidomimetics

Murru, Siva, Dooley, Colette T., Nefzi, Adel

Journal:

Tetrahedron Letters

Year:

2013

Language:

english

File:

PDF, 507 KB

english, 2013

26

Synthesis and biological evaluations of novel endomorphin analogues containing α-hydroxy-β-phenylalanine (AHPBA) displaying mixed μ/δ opioid receptor agonist and δ opioid receptor antagonist activities

Hu, Miao, Giulianotti, Marc A., McLaughlin, Jay P., Shao, Jiaan, Debevec, Ginamarie, Maida, Laura E., Geer, Phaedra, Cazares, Margaret, Misler, Jaime, Li, Ling, Dooley, Colette, Ganno, Michelle L., Ea

Journal:

European Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.08 MB

english, 2015

27

Altered secondary structure of Dynorphin A associates with loss of opioid signalling and NMDA-mediated excitotoxicity in SCA23

Smeets, Cleo J.L.M., Zmorzyńska, Justyna, Melo, Manuel N., Stargardt, Anita, Dooley, Colette, Bakalkin, Georgy, McLaughlin, Jay, Sinke, Richard J., Marrink, Siewert-Jan, Reits, Eric, Verbeek, Dineke S

Journal:

Human Molecular Genetics

Year:

2016

Language:

english

File:

PDF, 104 KB

english, 2016

28

A One-Pot Multicomponent Approach to a New Series of Morphine Derivatives and Their Biological Evaluation

Shao, Jiaan, Houghten, Richard A., Dooley, Colette T., Cazares, Margret, McLaughlin, Jay P., Eans, Shainnel O, Hoot, Michelle R., Ganno, Michelle L., Giulianott, Marc A., Yu, Yongping

Journal:

Organic & Biomolecular Chemistry

Year:

2017

Language:

english

File:

PDF, 920 KB

english, 2017

29

Fluorescent Mu Selective Opioid Ligands from a Mixture Based Cyclic Peptide Library

Li, Yangmei, Dooley, Colette T., Misler, Jaime A., Debevec, Ginamarie, Giulianotti, Marc A., Cazares, Margaret E., Maida, Laura, Houghten, Richard A.

Journal:

ACS Combinatorial Science

Year:

2012

Language:

english

File:

PDF, 2.04 MB

english, 2012

30

ChemInform Abstract: Synthesis and Screening of Positional Scanning Synthetic Combinatorial Libraries

Clemencia Pinilla, Jon R. Appel, Sylvie E. Blondelle, Colette T. Dooley, Jutta Eichler, Adel Nefzi, John M. Ostresh, Roland Martin, Darcy B. Wilson, Richard A. Houghten

Journal:

Year:

2001

File:

PDF, 25 KB

2001

31

De novo identification of highly active fluorescent kappa opioid ligands from a rhodamine labeled tetrapeptide positional scanning library

Richard A Houghten, Colette T Dooley, Jon R Appel

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 240 KB

english, 2004

32

Integrating computational and mixture-based screening of combinatorial libraries

Austin B. Yongye, Clemencia Pinilla, Jose L. Medina-Franco, Marc A. Giulianotti, Colette T. Dooley, Jon R. Appel, Adel Nefzi, Thomas Scior, Richard A. Houghten, Karina Martínez-Mayorga

Journal:

Journal of Molecular Modeling

Year:

2011

Language:

english

File:

PDF, 450 KB

english, 2011

33

A review of the utility of soluble peptide combinatorial libraries

Clemencia Pinilla, Jon Appel, Sylvie Blondelle, Colette Dooley, Barbara Dörner, Jutta Eichler, John Ostresh, Richard A. Houghten

Journal:

Year:

1995

Language:

english

File:

PDF, 2.09 MB

english, 1995

34

Orphanin FQ: Receptor binding and analog structure activity relationships in rat brain

Colette T. Dooley, Richard A. Houghten

Journal:

Year:

1996

Language:

english

File:

PDF, 529 KB

english, 1996

35

Direct Phenotypic Screening in Mice: Identification of Individual, Novel Antinociceptive Compounds from a Library of 734 821 Pyrrolidine Bis-piperazines

Houghten, Richard A., Ganno, Michelle L., McLaughlin, Jay P., Dooley, Colette T., Eans, Shainnel O., Santos, Radleigh G., LaVoi, Travis, Nefzi, Adel, Welmaker, Greg, Giulianotti, Marc A., Toll, Lawren

Journal:

ACS Combinatorial Science

Year:

2016

Language:

english

File:

PDF, 5.97 MB

english, 2016

36

Identification of Two Novel, Potent, Low-Liability Antinociceptive Compounds from the DirectIn VivoScreening of a Large Mixture-Based Combinatorial Library

Kate J. Reilley, Marc Giulianotti, Colette T. Dooley, Adel Nefzi, Jay P. McLaughlin, Richard A. Houghten

Journal:

The AAPS Journal

Year:

2010

Language:

english

File:

PDF, 614 KB

english, 2010

37

Parallel Synthesis of Hexahydrodiimidazodiazepines Heterocyclic Peptidomimetics and Their in Vitro and in Vivo Activities at μ (MOR), δ (DOR), and κ (KOR) Opioid Receptors

Eans, Shainnel O., Ganno, Michelle L., Mizrachi, Elisa, Houghten, Richard A., Dooley, Colette T., McLaughlin, Jay P., Nefzi, Adel

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.70 MB

english, 2015

38

A comparison of combinatorial library approaches for the study of opioid compounds

Colette T. Dooley, Richard A. Houghten

Journal:

Perspectives in Drug Discovery and Design

Year:

1995

Language:

english

File:

PDF, 1.26 MB

english, 1995

39

Toxicity of 6-hydroxydopamine: live cell imaging of cytoplasmic redox flux

Colette T. Dooley, Ling Li, Jaime A. Misler, Jane H. Thompson

Journal:

Cell Biology and Toxicology

Year:

2012

Language:

english

File:

PDF, 821 KB

english, 2012

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